Pancreatic Diseases and disorders

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Pancreatitis is generally divided into acute and chronic forms. Chronic pancreatitis describes a complex, highly variable and continuous inflammatory syndrome, defined by initially repetitive episodes of acute pancreatitis, which may develop into chronic pancreatitis in the further course. Progressive fibrosis of the pancreatic parenchyma, parenchymal calcifications and pancreatic ductal concretions ultimately lead to irreversible destruction of the organ due to the failure of exocrine and endocrine functions.

The risk of developing ductal adenocarcinoma of the pancreas is greatly increased.

Clinical signs include repeated attacks of abdominal pain with elevated serum levels of pancreatic enzymes, typical pancreatic pain, steatorrhea and diabetes mellitus. 

The incidence of chronic pancreatitis in industrialized countries is estimated at 3.5 to 10:100,000, with chronic alcohol abuse being the main cause. Other risk factors include genetic changes, hypertriglyceridemia, autoimmunity and hypercalcemia.

Early identification of individuals at risk can help establish the right clinical management

plan.

We offer comprehensive and syndrome-specific panels testing for pancreatic disorders.

The test can offer a molecular genetic diagnosis of a pancreatic disorder that is

observed or predicted in you or a family member.