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Neurological Disorders

The Neurological Disorders

Presented here encompass a wide range of disorders and symptoms, all related to the central nervous system and brain function. Symptoms that may occur during the course of the disorder include malfunction of the motor system, voluntary and involuntary movement, cognitive function and memory impairment.


Many disorders present themselves in childhood such as subtypes of Ataxia and Epilepsies, while others show increased prevalence with age and are related to the progressive degeneration of brain function, such as Alzheimer‘s disease.

Neurological Genetics

Some diseases can be caused by single gene defects, while others are more complex. Early identification of individuals at risk can help establish the right clinical management plan. Neurological disorders are often chronic, progressive, and debilitating, with phenotypes that are genetically heterogeneous Neurogenetic disorders are prominently seen in clinical genetics practice and have increased notably with the advent of molecular approaches. 


Next-generation DNA sequencing techniques have made it possible to examine a large number of possible disease genes in a single reaction, which was impossible to do with previous methods. This has resulted in the rapid identification of genes involved in Mendelian disorders, thereby making a precise diagnosis of many neurological disorders possible. Genetic testing for the same can be considered in the early stages of the diagnostic procedure.

Who needs to get tested?

  • Individuals presenting with symptoms of neurological disease
  • Individuals with family history of neurological disease
  • Individuals without a family history or sporadic presentation with symptoms associated with a specific neurological disease

What tests are available by Genatechs?

We offer comprehensive and syndrome-specific panels testing for neurological

disorders. The test can offer a molecular genetic diagnosis of a neurological disorder

that is observed or predicted in you or a family member. The genetic panels were

designed to cover various categories of neurological diseases including

Neurodegenerative, Neurocutaneous, Movement disorders, and Epilepsy

What tests are available by Genatechs?

We offer comprehensive and syndrome-specific panels testing for neurological

disorders. The test can offer a molecular genetic diagnosis of a neurological disorder

that is observed or predicted in you or a family member. The genetic panels were

designed to cover various categories of neurological diseases including

Neurodegenerative, Neurocutaneous, Movement disorders, and Epilepsy

Panels and Tests

Please reach us at contact@genatechs.com if you cannot find the test you are searching for. 

Single Gene


ATP1A2, CACNA1A, PRRT2, SCN1A


ACTB, ACTG1, ADGRG1, ARX, ATP6V0A2, B3GALNT2, B4GAT1, CDK5, DCX,

DYNC1H1, FKRP, FKTN, FTO, ISPD, KATNB1, KIAA1279, KIF2A, KIF5C, LAMA2,

LAMB1, LAMC3, LARGE, NDE1, OCLN, PAFAH1B1, PHGDH, POMGNT1, POMGNT2,

POMK, POMT1, POMT2, RAB18, RAB3GAP1, RAB3GAP2, RELN, RTTN, SNAP29,

SRD5A3, TBC1D20, TMEM5, TMTC3, TUBA1A, TUBA8, TUBB, TUBB2A, TUBB2B,

TUBB3, TUBB4A, TUBG1, VIPAS39, VLDLR, VPS33B, WDR62


ANKLE2, ARFGEF2, ASPM, ASXL3, ATR, ATRX, CASC5, CASK, CDC6, CDK5RAP2,

CDK6, CDKL5, CDT1, CENPE, CENPJ, CEP135, CEP152, CEP63, CIT, CRIPT, DIAPH1, DYRK1A, FOXG1, IER3IP1, KATNB1, KIF11, LIG4, MCPH1, MECP2, MED17, MFSD2A, MSMO1, NBN, NDE1, NHEJ1, NIN, ORC1, ORC4, ORC6, PCNT, PHC1, PLK4, PNKP, PPP1R15B, QARS, RAB18, RAB3GAP1, RAB3GAP2, RAD50, RBBP8, RTTN, SASS6, SLC25A19, SLC2A1, SLC9A6, STAMBP, STIL, TBC1D20, TCF4, TRAPPC9, TRMT10A, TSEN2, TSEN34, TSEN54, TUBGCP4, TUBGCP6, UBE3A, WDFY3, WDR62, XRCC4, ZEB2, ZNF335


ACTB, ACTG1, ADGRG1, AKT3, ARFGEF2, ARX, B3GALNT2, B4GAT1, CCND2, CDK5, COL4A1, COL4A2, DCX, DEPDC5, DYNC1H1, EMX2, ERMARD, FAT4, FIG4, FKRP, FKTN, FLNA, GMPPB, ISPD, KATNB1, KIAA1279, KIF2A, KIF5C, L1CAM, LAMB1, LARGE, MCPH1, NDE1, NEDD4L, OCLN, PAFAH1B1, PI4KA, PIK3CA, PIK3R2, POMGNT1, POMGNT2, POMK, POMT1, POMT2, RELN, RTTN, SHH, SIX3, SRPX2, TMEM5, TUBA1A, TUBA8, TUBB, TUBB2A, TUBB2B, TUBB3, TUBG1, WDR62


Single Gene


Single Gene


Single Gene


Single Gene


Single Gene


Single Gene


Single Gene


AMPD2, CASK, CHMP1A, CLP1, EXOSC3, EXOSC8, PCLO, RARS2, SEPSECS, TBC1D23, TOE1, TSEN15, TSEN2, TSEN34, TSEN54, VPS53, VRK1


Single Gene


CDKL5, FOXG1, MECP2, MEF2C


Single Gene


Single Gene


Single Gene


Single Gene


SLC52A2 & SLC52A3


Single Gene


Single Gene


Single Gene


Single Gene


Single Gene


Neurology-Neurodegenerative

MLC1, L2HGDH, D2HGDH, MLYCD


Single Gene


Single Gene


Single Gene


AIMP1, BCAP31, C11ORF73, DARS, EGR2, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, ERCC4, ERCC5, ERCC6, ERCC8, EXOSC8, FAM126A, GJC2, HSPD1, MLC1, MPZ, PLP1, POLR1C, POLR3A, POLR3B, PYCR2, RARS, SLC25A12, SLC33A1, SPTAN1, STXBP1, TBCD, TUBB4A, VPS11


Single Gene


Single Gene


Single Gene


AARS, AARS2, ABCD1, ABCD4, ACAD9, ACOX1, ACP5, ACSF3, ADAR, ADGRG1, ADSL, AGA, AGK, AIMP1, ALDH3A2, ALDH5A1, ALG1, ALG11, ALG12, ALG13, ALG2, ALG3, ALG6, ALG8, ALG9, AMT, ANO5, AP3B1, ARSA, ARSB, ASPA, ATP13A2, ATP6V0A2, ATP7A, B3GALNT2, B4GALT1, B4GAT1, BCAP31, BCKDHA, BCKDHB, BLOC1S6, BTD, C10orf2, CAD, CAPN3, CARS2, CAV3, CBS, CD27, CD320, CHKB, CLCN2, CLN3, CLN5, CLN6, CLN8, COG1, COG4, COG5, COG6, COG7, COG8, COL12A1, COL4A1, COL4A2, COL6A1, COL6A2, COL6A3, CSF1R, CTC1, CTSD, CTSF, CYP27A1, D2HGDH, DAG1, DARS, DARS2, DBT, DCAF17, DCAF8, DDC, DDOST, DES, DGUOK, DLAT, DLD, DMD, DNAJB6, DNAJC5, DOLK, DPAGT1, DPM1, DPM2, DPM3, DYSF, EARS2, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, EMD, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, ERCC8, ETFA, ETFB, ETFDH, FA2H, FAM126A, FARS2, FBXL4, FH, FHL1, FKRP, FKTN, FOLR1, FOXRED1, FUCA1, GALC, GALNS, GALT, GAN, GARS, GBE1, GCDH, GCSH, GFAP, GJA1, GJB1, GJC2, GLA, GLB1, GLDC, GM2A, GMPPB, GNPTAB, GNPTG, GNS, GPHN, GRN, GTF2H5, GUSB, HARS, HARS2, HCFC1, HEPACAM, HEXA, HGSNAT, HLCS, HMGCL, HNRNPDL, HSD17B4, HSPD1, HTRA1, HYAL1, IARS2, IDH2, IDS, IDUA, IFIH1, ISPD, ITGA7, ITK, IVD, JAM3, KARS, KCTD7, L2HGDH, LAMA2, LARGE, LARS, LARS2, LIAS, LMBRD1, LMNA, LMNB1, LYST, MAN2B1, MANBA, MARS, MARS2, MCCC1, MCCC2, MCEE, MCOLN1, MFSD8, MGAT2, MGME1, MLC1, MLYCD, MMAA, MMAB, MMACHC, MMADHC, MOCS1, MOCS2, MOGS, MPDU1, MPI, MPLKIP, MPV17, MTHFR, MTR, MTRR, MUT, MYOT, NAGLU, NARS2, NDUFA1, NDUFA11, NDUFA12, NDUFA2, NDUFA9, NDUFAF1, NDUFAF2, NDUFAF3, NDUFAF4, NDUFAF5, NDUFAF6, NDUFB3, NDUFB9, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS6, NDUFS8, NDUFV1, NDUFV2, NEU1, NOTCH3, NPC1, NPC2, NUBPL, OCLN, OCRL, OPA1, PABPN1, PAH, PC, PCCA, PCCB, PDHA1, PDHB, PDHX, PDK3, PDP1, PDX1, PEX1, PEX10, PEX11B, PEX12, PEX13, PEX14, PEX16, PEX19, PEX2, PEX26, PEX3, PEX5, PEX6, PEX7, PGM1, PHGDH, PHYH, PLEC, PLP1, PMM2, POLG, POLR1C, POLR3A, POLR3B, POMGNT1, POMGNT2, POMK, POMT1, POMT2, PPT1, PRF1, PRPS1, PSAP, PYCR2, QARS, QDPR, RAB27A, RARS, RARS2, RFT1, RNASEH2A, RNASEH2B, RNASEH2C, RNASET2, RNF113A, RPIA, RRM2B, SAMHD1, SARS2, SCP2, SEPN1, SGCA, SGCB, SGCD, SGCG, SH2D1A, SLC16A2, SLC17A5, SLC25A1, SLC25A12, SLC25A4, SLC35A1, SLC35A2, SLC35C1, SLC7A7, SMCHD1, SOX10, SPG11, SRD5A3, SSR4, STT3A, STT3B, STX11, STXBP2, SUCLA2, SUCLG1, SUGCT, SUOX, SYNE1, SYNE2, TARS2, TCAP, TK2, TMEM165, TMEM43, TMEM5, TNPO3, TPP1, TRAPPC11, TREM2, TREX1, TRIM32, TTN, TUBB4A, TYMP, TYROBP, UNC13D, VARS2, XIAP, YARS, YARS2, ZFYVE26


ARSA, PSAP


Single Gene


Single Gene


Single Gene


ATP13A2, COASY, C19orf12, CP, DCAF17, FA2H, FTL, PANK2, PLA2G6, WDR45


POLR3A, POLR3B


Single Gene


AHI1, ARL13B, B9D1, C2CD3, C5orf42, CC2D2A, CEP104, CEP290, CEP41, CSPP1, DDX59, INPP5E, KIAA0556, KIAA0586, KIAA0753, KIF7, LAMA1, MKS1, NPHP1, OFD1, PDE6D, RPGRIP1L, TCTN1, TCTN2, TCTN3, TMEM138, TMEM216, TMEM231, TMEM237, TMEM67, TTC21B, ZNF423


ATP13A2, CLN3, CLN5, CLN6, CLN8, CTSD, CTSF, DNAJC5, GRN, KCTD7, MFSD8, PPT1, TPP1


Single Gene


Single Gene


Single Gene


Single Gene


CLN3, PPT1, TPP1


Single Gene


Single Gene


📍Jabal Amman-5th Circle-Opposite of Arab Medical Center Hospital

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